lavendustin B

SKU: orb1303082

Description

Lavendustin B is a dual-function small molecule that acts as a tyrosine kinase inhibitor and disrupts the HIV-1 integrase-LEDGF/p75 protein-protein interaction. This compound is utilized in biochemical and cellular assays to study kinase signaling and HIV-1 replication mechanisms in vitro.

Research Area

Infectious Disease & Virology, Metabolism Research, Protein Biochemistry

Key Properties

• CAS Number: 125697-91-8
• MW: 365.38
• Purity: 96.13% (May vary between batches)
• Formula: C₂₁H₁₉NO₅
• SMILES: OC(=O)c1cc(ccc1O)N(Cc1ccccc1O)Cc1ccccc1O
• Target: HIV Protease,Tyrosinase,transporter
• Solubility: DMSO:65 mg/mL (177.9 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.47 mM)

Bioactivity

• Target IC50:
  HIV-1 integrase-LEDGF/p75:94.07 μM (IC50)|GLUT1:15 μM (Ki)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

ATP-competitive, p75, inhibit, Inhibitor, integrase, LEDGF, lavendustin B, HIVProtease, HIV-1, HIV-1 integrase, HIV Protease, HIV Integrase, GLUT, GLUT1, Glucose transporter, Tyrosine Kinase, Tyrosinase

Compound Identifiers

PubChem CID

3895