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Catalog Number | orb1089476 |
---|---|
Category | Small Molecules |
Description | Lasmiditan, also known as COL-144 and LY573144, is a novel, centrally acting, highly selective 5-HT(1F) receptor agonist (K1=2.21 μM) without vasoconstrictor activity that seemed effective when given as an intravenous infusion in a proof-of-concept migraine study. Lasmiditan showed efficacy in its primary endpoint, with a 2-hour placebo-subtracted headache response of 28.8%, though with frequent reports of dizziness, paresthesias, and vertigo. |
CAS Number | [613677-28-4] |
MW | 413.821274 |
SMILES | O=C(C1C(F)=CC(F)=CC=1F)NC1C=CC=C(C(=O)C2CCN(C)CC2)N=1.[H]Cl |
Formula | C19H19CLF3N3O2 |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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