Lasmiditan HCl

• Catalog Number: orb1089476
• Category: Small Molecules
• Description: Lasmiditan, also known as COL-144 and LY573144, is a novel, centrally acting, highly selective 5-HT(1F) receptor agonist (K1=2.21 μM) without vasoconstrictor activity that seemed effective when given as an intravenous infusion in a proof-of-concept migraine study. Lasmiditan showed efficacy in its primary endpoint, with a 2-hour placebo-subtracted headache response of 28.8%, though with frequent reports of dizziness, paresthesias, and vertigo.
• MW: 413.82127404213
• CAS Number: 613677-28-4
• Formula: C₁₉H₁₉CLF₃N₃O₂
• SMILES: O=C(C1C(F)=CC(F)=CC=1F)NC1C=CC=C(C(=O)C2CCN(C)CC2)N=1.[H]Cl
• Note: For research use only
• Expiration Date: 12 months from date of receipt.