LasB-IN-1

SKU: orb3132814

Description

LasB-IN-1 (compound 5f) is an efficient and orally active inhibitor of LasB (IC50 = 8.7 μM). It effectively inhibits elastase production and biofilm formation in Pseudomonas aeruginosa, while also attenuating inflammatory responses by downregulating MAPK and NF-κB pathways. LasB-IN-1 holds potential as a candidate agent against drug-resistant infections.

Research Area

Infectious Disease & Virology, Protein Biochemistry, Signal Transduction

Key Properties

• Formula: C₂₀H₂₂F₃NO₂
• Target: Serine Protease,Antibacterial,p38 MAPK,NF-κB

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Serine Protease,Antibacterial,p38 MAPK,NF-κB