Lartesertib

SKU: orb1687359

Description

Lartesertib is a potent and selective ATM kinase inhibitor used in cancer research. It is employed in vitro and in vivo to study DNA damage response pathways, particularly in the context of non-small cell lung cancer and other malignancies.

Research Area

Cell Biology, Immunology & Inflammation, Molecular Biology, Signal Transduction

Key Properties

• CAS Number: 2495096-26-7
• MW: 448.45
• Purity: 99.90% (May vary between batches)
• Formula: C₂₃H₂₁FN₆O₃
• SMILES: COc1cncc(F)c1-n1c2c(cnc3cc(OC)c(cc23)-c2cn(C)nc2C)n(C)c1=O
• Target: STING,PD-1/PD-L1,ATM/ATR
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.36 mM);DMSO:80 mg/mL (178.39 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

ATR, ATM Inhibitor-5, ATM, M4076

Compound Identifiers

PubChem CID

122599280