Larsucosterol trimethylamine

SKU: orb1983172

Description

Larsucosterol trimethylamine (DUR-928) is a liver X receptor (LXR) antagonist with epigenetic modulatory activity. It reduces hepatic lipid accumulation, suppresses LPS- and TNFα-driven inflammation in macrophages, and demonstrates protective effects in models of LPS- and acetaminophen-induced organ injury.

Research Area

Metabolism Research

Key Properties

• Target: Liver X Receptor,Endogenous Metabolite
• Molecular Weight: 541.83
• Purity: 97.00%
• Formula: C₃₀H₅₅NO₅S
• SMILES: C[C@@H]([C@H]1CC[C@@H]2[C@]1(C)CC[C@H]3[C@H]2CC=C4[C@]3(C)CC[C@H](OS(=O)(O)=O)C4)CCCC(C)(O)C.CN(C)C

Storage & Handling

• Storage: store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

DV-928 trimethylamine, DUR-928 trimethylamine, LXR, Liver X Receptor, LiverXReceptor

Compound Identifiers

PubChem CID

166638328