Larotinib mesylate hydrate

SKU: orb1745060

Description

Larotinib mesylate hydrate is a potent and orally bioavailable tyrosine kinase inhibitor with broad-spectrum activity, notably targeting EGFR with high potency (IC50 = 0.6 nM). It is widely used in preclinical research for investigating EGFR-driven cancers, demonstrating efficacy in both in vitro cellular assays and in vivo xenograft models.

Research Area

Cardiovascular Research, Immunology & Inflammation, Signal Transduction

Key Properties

• CAS Number: 2097129-93-4
• MW: 699.17
• Formula: C₂₆H₃₆ClFN₄O₁₁S₂
• SMILES: CS(=O)(O)=O.COC(C(OCCCN1C[C@]2([H])[C@](OCCO2)([H])C1)=C3)=CC4=C3C(NC5=CC(Cl)=C(C=C5)F)=NC=N4.CS(=O)(O)=O.O
• Target: IRAK,Others,BTK,EGFR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

168006954