Lapatinib tosylate

SKU: orb1744815

Description

Lapatinib ditosylate is an orally bioavailable, dual tyrosine kinase inhibitor targeting EGFR and ErbB-2 (HER2) with IC50 values of 10.2 nM and 9.8 nM, respectively. It is widely used in vitro and in vivo for cancer research, particularly in studies of breast cancer and other HER2/EGFR-driven malignancies.

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Key Properties

• CAS Number: 1187538-35-7
• MW: 753.26
• Formula: C₃₆H₃₄ClFN₄O₇S₂
• SMILES: O=S(=O)(O)C1=CC=C(C=C1)C.O=S(=O)(C)CCNCC=1OC(=CC1)C=2C=CC3=NC=NC(NC4=CC=C(OCC=5C=CC=C(F)C5)C(Cl)=C4)=C3C2
• Target: EGFR,Ferroptosis,Autophagy,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

11679357