Lanabecestat HCl

SKU: orb1738673

Description

Lanabecestat (AZD3293/LY3314814) is an orally bioavailable, brain-penetrant BACE1 inhibitor with slow off-rate kinetics. It has demonstrated dose- and time-dependent lowering of Aβ peptides in plasma, CSF, and brain in preclinical studies, supporting its investigation for Alzheimer's disease research in both in vitro and in vivo models.

Research Area

Neuroscience

Key Properties

• CAS Number: 1383986-31-9
• MW: 448.995
• Formula: C₂₆H₂₉ClN₄O
• SMILES: Cl.CO[C@H]1CC[C@@]2(Cc3ccc(cc3[C@@]22N=C(C)C(N)=N2)-c2cncc(c2)C#CC)CC1
• Target: Beta-Secretase,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171360863