Lalistat 2

SKU: orb1303145

Description

Lalistat 2 is a potent and selective lysosomal acid lipase (LAL) inhibitor with an IC50 of 152 nM, showing no activity against related lipases up to 10 µM. This tool compound is valuable for investigating LAL's role in lipid metabolism, lysosomal storage disorders, and atherosclerosis in both cellular and animal models.

Research Area

Metabolism Research

Key Properties

• CAS Number: 1234569-09-5
• MW: 296.39
• Purity: 98.30% (May vary between batches)
• Formula: C₁₃H₂₀N₄O₂S
• SMILES: O=C(Oc1nsnc1N1CCCCC1)N1CCCCC1
• Target: Lipase
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.75 mM);DMSO:50 mg/mL (168.7 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

cholesteryl ester storage disease, dried blood spot, Inhibitor, Lalistat 2, Lalistat2, Lalistat-2, inhibit, lysosomal acid lipase, lysosomal acid lipase deficiency

Compound Identifiers

PubChem CID

46867138