LAG-3 cyclic peptide inhibitor 12

SKU: orb2942799

Description

Cyclic peptide 12 is a potent and selective LAG-3 inhibitor with a Ki of 2.66 µM and an IC50 of 4.45 µM. This cell-permeable compound is a valuable tool for in vitro studies of LAG-3 function in T-cell regulation and cancer immunotherapy research.

Research Area

Immunology & Inflammation, Immunology & Inflammation; Pharmacology & Drug Discovery

Key Properties

• Target: LAG-3
• MW: 1050.28
• Formula: C₄₄H₆₇N₁₃O₁₁S₃
• SMILES: C[C@H]1C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@H](C(=O)N2CCC[C@H]2C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1)CCCN=C(N)N)CC3=CC(=CC=C3)C#N)[C@@H](C)O)CCSC)C(C)C)N)C(=O)O

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172677241