L-Thyroxine

SKU: orb1310221

Description

L-Thyroxine (NSC 36397), the primary thyroid hormone, is biosynthesized from iodinated tyrosine residues within thyroglobulin. It is a prohormone that is secreted and peripherally deiodinated to the active triiodothyronine (T3), making it essential for research into thyroid function, metabolic regulation, and endocrine signaling in both in vitro and in vivo models.

Research Area

Metabolism Research

Key Properties

• CAS Number: 51-48-9
• MW: 776.87
• Purity: 99.56%
• Formula: C₁₅H₁₁I₄NO₄
• SMILES: N[C@@H](Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C(O)=O
• Target: Endogenous Metabolite,Thyroid hormone receptor(THR)
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (4.25 mM);H2O:< 1 mg/mL (insoluble or slightly soluble);Ethanol:< 1 mg/mL (insoluble or slightly soluble);DMSO:93 mg/mL (119.71 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

NSC 36397, NSC-36397, NSC36397, LThyroxine, L-Thyroxine, L Thyroxine, inhibit, Inhibitor, Levothyroxine, EndogenousMetabolite, Endogenous Metabolite, T 4, T-4, T4, Thyroid hormone, Thyroid hormone receptor, Thyroid Hormone Receptor, Thyroid hormone receptor(THR), Thyroidhormonereceptor(THR), Thyroidhormonereceptor, THR

Compound Identifiers

PubChem CID

5819