L-Methionine-DL-sulfoximine

SKU: orb1303122

Description

L-Methionine-DL-sulfoximine (MSO) is a potent glutamine synthetase inhibitor that selectively targets astroglia, inducing distinct metabolic and morphological changes. It is widely used as a chemical tool in convulsant research, facilitating studies of epilepsy mechanisms and astrocyte function in both in vivo and in vitro experimental models.

Research Area

Pharmacology & Drug Discovery, Protein Biochemistry

Key Properties

• CAS Number: 15985-39-4
• MW: 180.225
• Purity: 99.82% (May vary between batches)
• Formula: C₅H₁₂N₂O₃S
• SMILES: O=C(O)[C@@H](N)CCS(=N)(C)=O
• Target: Glutaminase,Others
• Solubility: DMSO:< 1.8 mg/mL (10 mM, insoluble or slightly soluble);H2O:47.73 mg/mL (264.83 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

LMethionineDLsulfoximine, L-Methionine-DL-sulfoximine, L Methionine DL sulfoximine, MSX, MSO, inhibit, glutamine synthetase, Inhibitor

Compound Identifiers

PubChem CID

89034