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L-Kynurenine

SKU: orb1221368

Description

L-Kynurenine is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase KMO and KAT associated with the suppression of antitumor immune responses. It has been shown to inhibit allogeneic T-cell proliferation and to increase malignant U87 glioma cell invasion into a collagen matrix.

Images & Validation

Key Properties

CAS Number2922-83-0
MW208.21
Purity>98% (HPLC)
FormulaC10H12N2O3
SMILESN[C@@H](CC(=O)c1ccccc1N)C(O)=O
TargetEndogenous Metabolite
SolubilityDMSO:50 mg/mL (240.14 mM) Need ultrasonic;Water:4mg/mL(at 20°C);0.5M HCL:50mg/mL

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

(S)-Kynurenine

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L-Kynurenine (orb1221368)

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