L-Carnitine hydrochloride

SKU: orb1227181

Description

Constituent of striated muscle and liver. It is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias. (In Vitro):When expressed in human embryonic kidney (HEK)293 cells, hOCTN2 (SLC22A5) shows low but significant stereospecific transport activity: D-carnitine is transported with lower affinity (Km=10.9 μM) than the L-isomer (Km=4.3 μM).

Key Properties

• CAS Number: 10017-44-4
• MW: 197.66
• Purity: >98% (HPLC)
• Formula: C₇H₁₅NO₃·HCl
• SMILES: C[N+](C)(C)C[C@H](CC(=O)O)O.[Cl-]
• Target: CRAT
• Solubility: DMSO: > 10 mM

Bioactivity

• In Vitro:
  When expressed in human embryonic kidney (HEK)293 cells, hOCTN2 (SLC22A5) shows low but significant stereospecific transport activity: D-carnitine is transported with lower affinity (Km=10.9 μM) than the L-isomer (Km=4.3 μM).
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Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

CRAT