L-Buthionine-(S,R)-sulfoximine hydrochloride

SKU: orb1909016

Description

L-Buthionine-(S,R)-sulfoximine hydrochloride is a cell-permeable, irreversible inhibitor of γ-glutamylcysteine synthetase (γ-GCS), leading to glutathione depletion. It is widely used in cancer research, with in vitro studies showing activity against melanoma, breast, and ovarian tumor specimens, and in vivo models for investigating oxidative stress pathways.

Research Area

Cell Biology

Key Properties

• MW: 258.77
• Formula: C₈H₁₉ClN₂O₃S
• Target: Ferroptosis,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Ferroptosis,Others