L-4-Aminoarabinose-bactoprenyl phosphate

SKU: orb3181825

Description

L-4-Aminoarabinose-bactoprenyl phosphate (L-4-Aminoarabinose-BP) serves as a substrate for the ArnT enzyme, playing a key role in the covalent modification of lipid A. It facilitates the transfer of L-4-aminoarabinose (Ara4N) to the lipid A segment of lipopolysaccharides (LPS), enabling the cationic modification of lipid A and thus conferring resistance to cationic antimicrobial peptides (CAMPs) in Gram-negative bacteria. This endogenous intermediate is synthesized intracellularly by a series of enzymes encoded by the arn operon, such as ArnC and ArnD, in Gram-negative organisms like Escherichia coli.

Research Area

Metabolism Research

Key Properties

• CAS Number: 402491-79-6
• MW: 978.43
• Formula: C₆₀H₁₀₀NO₇P
• SMILES: O(P(OC/C=C(\CC/C=C(\CC/C=C(\CC/C=C(\CC/C=C(\CC/C=C(\CC/C=C(\CC/C=C(\CC/C=C(/CC/C=C(/CCC=C(C)C)\C)\C)/C)/C)/C)/C)/C)/C)/C)/C)(=O)O)[C@H]1[C@H](O)[C@@H](O)[C@@H](N)CO1
• Target: Endogenous Metabolite

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Endogenous Metabolite