KY386

SKU: orb1942799

Description

KY386 is a potent and selective DHX33 helicase inhibitor (IC50 = 19 nM) with demonstrated anti-cancer activity in DHX33-overexpressing U251-MG glioblastoma cells (IC50 = 20 nM). It shows moderate metabolic stability and is a useful research tool for investigating DHX33's role in cancer cell proliferation and as a potential therapeutic target in oncology research.

Research Area

Cell Biology, Molecular Biology

Key Properties

• CAS Number: 2787598-01-8
• MW: 405.47
• Formula: C₂₁H₁₉N₅O₂S
• SMILES: N#CC=1C=C(SC1N2C(=CC(C(=O)NC3=NC=4C=CC(OC)=CC4N3)=C2C)C)C
• Target: Others,DNA/RNA Synthesis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

166058639