Kushenol Z

SKU: orb3211878

Description

Kushenol Z is a cAMP-PDE/Akt inhibitor. It reduces the activity of cAMP phosphodiesterase, elevates cAMP levels, and boosts PKA activity while inhibiting the mTOR pathway by decreasing the phosphorylation of Akt and PRAS40. Additionally, Kushenol Z induces apoptosis (apoptosis) in non-small cell lung cancer cells through mitochondrial and endoplasmic reticulum stress pathways, upregulating CHOP, modulating the Bax/Bcl-2 ratio, and activating caspases-3/7/9/12. Kushenol Z is suitable for research related to non-small cell lung cancer.

Key Properties

• CAS Number: 2467875-82-5
• MW: 436.50
• Formula: C₂₆H₂₈O₆
• SMILES: O=C1C(O)=C(OC2=C1C(OC)=CC(O)=C2CC(C(=C)C)CC=C(C)C)C=3C=CC(O)=CC3
• Target: PDE,PKA,Akt,Bcl-2 Family,mTOR,Apoptosis,Caspase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

PDE,PKA,Akt,Bcl-2 Family,mTOR,Apoptosis,Caspase