KUNG65

SKU: orb2665358

Description

KUNG65 is a potent and selective small molecule inhibitor of Grp94 (Hsp90B1) with a K_d of 540 nM, showing over 73-fold selectivity versus other Hsp90 isoforms. This tool compound is useful for studying Grp94-specific biology in cancer, inflammation, and autoimmune disease research, both in cellular and biochemical assays.

Research Area

Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 2144469-30-5
• MW: 414.85
• Formula: C₂₃H₂₀ClFO₄
• SMILES: O=C(OC)C=1C(O)=CC(O)=C(Cl)C1CCC=2C=CC=CC2CC3=CC=C(F)C=C3
• Target: HSP

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

131704472