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KUNB106

SKU: orb3173579

Description

KUNB106 is a selective inhibitor of Hsp90β with a KD value of 91 nM. It inhibits Hsp90β and Hsp90α with IC50 values of 38 μM and 91 nM, respectively. KUNB106 exhibits antiproliferative activity against MDA-MB-231 cells, A549 cells, and SKOV-3 cells, making it useful for research in triple-negative breast cancer.

Research Area

Metabolism Research, Signal Transduction

Images & Validation

Key Properties

CAS Number2393980-27-1
MW462.59
FormulaC27H34N4O3
SMILESO=C1NC(=CC=2C=C(C=C(C12)N3CCC(O)CC3)N4N=C(C=5C(=O)CC(C)(C)CC54)C)CCC
TargetHSP

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information