KU-0058948

SKU: orb1740744

Description

KU-0058948 is a potent and selective PARP inhibitor. It has been shown to induce cell cycle arrest and apoptosis in primary myeloid leukemic cells and established leukemic cell lines in vitro. Its mechanism supports research in oncology, particularly for studying DNA damage response and potential therapeutic strategies in hematological malignancies.

Research Area

Cell Biology, Epigenetics & Chromatin, Molecular Biology

Key Properties

• CAS Number: 763111-49-5
• MW: 380.42
• Formula: C₂₁H₂₁FN₄O₂
• SMILES: C(C=1C=2C(C(=O)NN1)=CC=CC2)C3=CC(C(=O)N4CCCNCC4)=C(F)C=C3
• Target: Apoptosis,Others,PARP

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

11291932