KRL74

SKU: orb2813704

Description

KRL74 is a cyclic peptide inhibitor that disrupts the HIV-1 Gag p6/TSG101 UEV interaction (Kd 11.9 µM), inhibiting viral budding with an IC50 of 2 µM in VLP assays. It serves as a valuable research tool for studying the late stages of HIV-1 replication in vitro.

Research Area

Infectious Disease & Virology, Protein Biochemistry

Key Properties

• Target: HIV Protease,Others
• CAS Number: 2423969-43-9
• MW: 981.53
• Formula: C₅₀H₆₁ClN₁₀O₉
• SMILES: C(C=1C=2C(NC1)=CC=CC2)[C@@H]3NC(=O)[C@H](CC4=CC=C(Cl)C=C4)NC(=O)[C@]([C@H](CC)C)(NC(=O)[C@H](CC=5C=6C(NC5)=CC=CC6)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](C(C)C)NC(=O)[C@H](C)NC3=O)[H]

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172677520