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KRAS inhibitor-41

SKU: orb3028341

Description

KRAS inhibitor-41 is a KRAS inhibitor with an IC50 value of less than 0.01 μM for both KRAS G12D and KRAS G12V mutations. It effectively inhibits RAS mutant cell lines GP2D (KRAS-G12D) and SW620 (KRAS-G12V). KRAS inhibitor-41 is applicable for cancer research.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

CAS Number3056974-50-3
MW604.745
FormulaC30H37FN10OS
SMILESC(#N)C=1C=2C3(CN(C3)C=4N=C(N([C@H](C)C5=C(N)N=CC=C5)CC)N=C(OC[C@@]67N(C[C@H](F)C6)CCC7)N4)CCC2SC1N
TargetRas

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information