KRAS inhibitor-40

SKU: orb2945570

Description

KRAS inhibitor-40 is a small molecule that disrupts the KRAS G12C-BRAF complex, inhibiting downstream ERK signaling and tumor cell proliferation. It is used in cancer research, particularly for studying KRAS-driven tumors, and has demonstrated activity in both in vitro cellular assays and in vivo xenograft models.

Research Area

Cell Biology, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 3059496-56-6
• MW: 1100.66
• Formula: C₅₃H₆₆ClF₄N₉O₈S
• SMILES: O=C1OCC(C)(C)CC=2C=3C=C(C=C4C3N(C2C5=CC(=CN=C5C(OC)C)N6CCOCC6)CC(F)(F)C4)C=7N=C(SC7)CC(NC(=O)C(N(C(=O)C8(F)CCN(C(=O)C(F)Cl)CC8)C)C(C)C)C(=O)N9NC1CCC9
• Target: Ras,Kras,PERK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

176455467