KRAS inhibitor-31

SKU: orb2665546

Description

KRAS inhibitor-31 (compound 33) is a highly potent small molecule binder of KRAS G12D, G12C, and G12V mutants, with SPR-measured K D values of 0.019 nM, 0.019 nM, and 0.096 nM, respectively. This tool compound is suitable for in vitro biochemical and cellular studies of oncogenic KRAS signaling and inhibition.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 2920695-77-6
• MW: 617.62
• Formula: C₃₃H₃₀F₃N₅O₄
• SMILES: FC=1C=2C3=C(N4[C@](COC3=NC1C=5C6=C(C=C(O)C5)C=CC(F)=C6C#C)(COCCC4)[H])N=C(OC[C@@]78N(C[C@H](F)C7)CCC8)N2
• Target: Ras

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172420098