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KRAS inhibitor-15

SKU: orb1687306

Description

KRAS inhibitor-15 is a potent and selective KRAS G12C inhibitor with an IC50 of 0.954 µM. It effectively inhibits p-ERK signaling in cellular models such as MIA PaCA-2 cells, supporting its research application in pancreatic, colorectal, and non-small cell lung cancer studies.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

CAS Number2230873-75-1
MW451.34
FormulaC20H17Cl2FN4OS
SMILESFC=1C=2C(=C(SN2)N3CCN(C(C=C)=O)CC3)C=C(Cl)C1C4=C(Cl)C=CC(N)=C4
TargetOthers,Kras,Ras

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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KRAS inhibitor-15 (orb1687306)

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