KRAS inhibitor-15

SKU: orb1687306

Description

KRAS inhibitor-15 is a potent and selective KRAS G12C inhibitor with an IC50 of 0.954 µM. It effectively inhibits p-ERK signaling in cellular models such as MIA PaCA-2 cells, supporting its research application in pancreatic, colorectal, and non-small cell lung cancer studies.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 2230873-75-1
• MW: 451.34
• Formula: C₂₀H₁₇Cl₂FN₄OS
• SMILES: FC=1C=2C(=C(SN2)N3CCN(C(C=C)=O)CC3)C=C(Cl)C1C4=C(Cl)C=CC(N)=C4
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

135148832