KRAS inhibitor-13

SKU: orb1686876

Description

KRAS inhibitor-13 is a potent and selective KRAS G12C inhibitor with an IC50 of 0.883 µM. It demonstrates downstream p-ERK inhibition in cellular models such as MIA PaCa-2 cells, supporting its research utility in pancreatic, colorectal, and non-small cell lung cancer studies.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 2230873-96-6
• MW: 479.95
• Formula: C₂₅H₁₉ClFN₃O₂S
• SMILES: C(C=C)(=O)N1[C@@]2([C@@](N(C2)C3=C4C(=NS3)C(F)=C(C(Cl)=C4)C=5C6=C(C=C(O)C5)C=CC=C6)(CC1)[H])[H]
• Target: Kras,Others,Ras

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

135148687