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KRAS IN-44

SKU: orb3135080

Description

KRAS IN-44 (Compound S2C2M2) is a PDE6D degrader. It inhibits PDE6D-dependent KRAS transport and downstream signaling pathways. Additionally, KRAS IN-44 downregulates EGF-induced phosphorylation of PI3K, AKT, and mTOR. It promotes apoptosis and exhibits antitumor activity against hepatoblastoma.

Research Area

Cell Biology, Metabolism Research, Signal Transduction

Images & Validation

Key Properties

TargetPI3K,Akt,mTOR,Ras,Apoptosis,PDE

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information