KRAS G12D inhibitor 26

SKU: orb2944433

Description

Compound 64B is a potent and selective KRAS G12D inhibitor with an IC50 of ≤100 nM. It is a valuable research tool for investigating KRAS-driven oncogenesis in both cellular assays and in vivo models, supporting the development of targeted cancer therapies.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 2972625-49-1
• MW: 663.23
• Purity: 99.93% (May vary between batches)
• Formula: C₃₅H₄₄ClFN₈O₂
• SMILES: CN1[C@]2(C=3C(CCC2)=CC=CC3)CC=4C(C1)=C(N=C(OC[C@@]56N(C[C@H](F)C5)CCC6)N4)N7CC=8N(CCC7)N=C(C(N(C)C)=O)C8Cl
• Target: Kras,Ras
• Solubility: DMSO:80 mg/mL (120.62 mM);10% DMSO+90% Corn Oil:3.3 mg/mL (4.98 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

169145642