KRAS G12D inhibitor 16

SKU: orb1744952

Description

KRAS G12D Inhibitor 16 is a highly potent small molecule targeting the KRAS G12D mutation, with IC50 values of 0.7 nM and 0.35 μM for the mutant and wild-type proteins, respectively. It is a valuable research tool for studying KRAS-driven cancers such as pancreatic, colorectal, and non-small cell lung carcinomas in both in vitro and in vivo models.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 2648221-12-7
• MW: 682.59
• Formula: C₃₂H₃₉IN₆O₃
• SMILES: C(C1(COC2=NC(=C3C(=N2)CN(CC3)C=4C5=C(C=C(O)C4)C=CC=C5I)N6CC7NC(C6)CC7)CC1)N8CCOCC8
• Target: Others,Ras,Kras

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

156405061