KRAS G12C inhibitor 50

SKU: orb1686147

Description

This small molecule compound is a potent and selective inhibitor of the KRAS G12C mutant protein, exhibiting an IC50 of 46.7 nM. It is a valuable research tool for investigating targeted cancer therapies in both in vitro biochemical assays and in vivo preclinical models of KRAS G12C-driven cancers.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 2760354-12-7
• MW: 550.65
• Formula: C₃₁H₃₄N₈O₂
• SMILES: C(C=1N2C(C(=NC(OC[C@@H]3CCCN3C)=N2)N4C[C@H](CC#N)N(C(C=C)=O)CC4)=NC1)C=5C6=C(C=CC5)C=CC=C6
• Target: Kras,Others,Ras

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

163206602