KRAS G12C inhibitor 47

SKU: orb1686174

Description

This potent and selective KRAS G12C inhibitor (IC50: 0.172 μM) demonstrates strong p-ERK inhibition in cellular models like MIA PaCa-2 cells. It is a valuable research tool for investigating targeted therapies in pancreatic, colorectal, and non-small cell lung cancers, supporting both in vitro and in vivo oncology studies.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 2253119-24-1
• MW: 547.02
• Formula: C₃₀H₂₈ClFN₄O₃
• SMILES: O=C1N(C=2C(C(=N1)N3CCN(C(C=C)=O)CC3)=CC(Cl)=C(C2)C4=C(F)C=CC=C4O)C5=C(C(C)C)C=CC=C5
• Target: Others,Ras,Kras

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

137297882