KRAS G12C inhibitor 43

SKU: orb1685954

Description

This small molecule is a potent and selective KRAS G12C inhibitor, demonstrating sub-micromolar IC50 values against H358 cell proliferation and migration. It serves as a valuable research tool for investigating KRAS-driven oncogenesis in both in vitro and in vivo models, supporting studies in cancer biology and targeted therapy development.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 2648808-69-7
• MW: 577.68
• Formula: C₃₃H₃₅N₇O₃
• SMILES: O(C[C@H]1N(C)CCC1)C=2N=C(C3=C(N=C(C=C3)C=4C5=C(C=C(OC)C4)C=CC=C5)N2)N6C[C@H](CC#N)N(C(C=C)=O)CC6
• Target: Kras,Others,Ras

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

163408777