KRAS G12C inhibitor 28

SKU: orb1744968

Description

KRAS G12C Inhibitor 28 is a potent and selective small molecule targeting the KRAS G12C mutation, demonstrating an IC50 of 57 nM. It is a valuable research tool for investigating KRAS-driven oncogenesis in both cellular and animal models of cancer, supporting preclinical drug discovery efforts.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 2649004-88-4
• MW: 635.64
• Formula: C₃₃H₃₆F₂N₅O₄P
• SMILES: O=C1N(C=2C(C(=N1)N3[C@@H](C)CN(C(C=C)=O)CC3)=CC(F)=C(N2)C4=C(F)C=CC=C4O)C5=C(C(C)C)C=C(P(C)(C)=O)C=C5C
• Target: Ras,Kras,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

156443495