KRAS G12C inhibitor 19

SKU: orb1690700

Description

KRAS G12C inhibitor 19 is a potent and selective small molecule targeting the KRAS G12C mutation. It demonstrates robust anti-proliferative activity in vitro and has shown efficacy in inhibiting tumor growth in vivo, making it a valuable tool for oncology research focused on RAS-driven cancers.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 2649788-46-3
• MW: 528.96
• Purity: 98.31% (May vary between batches)
• Formula: C₂₅H₁₉ClF₂N₄O₃S
• SMILES: C(#N)C=1C2=C(C=CC(F)=C2SC1N)C=3C(Cl)=C4C(=CC3F)C(=O)N5[C@@](CCO4)(CN(C(C=C)=O)CC5)[H]
• Target: Ras,Kras
• Solubility: DMSO:52.9 mg/mL (100.01 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:10 mg/mL (18.91 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

KRAS G12C, KRAS G12C inhibitor 19, KRAS G-12C inhibitor 19

Compound Identifiers

PubChem CID

156472638