KRAS G12C-IN-70

SKU: orb3135011

Description

KRAS G12C-IN-70 is a selective inhibitor targeting the KRAS G12C mutant. It disrupts downstream signaling pathways mediated by KRAS G12C, such as RAF-MEK-ERK, thereby inhibiting tumor cell proliferation. KRAS G12C-IN-70 is a promising candidate for research related to tumors associated with KRAS G12C mutations, including non-small cell lung cancer and colorectal cancer.

Research Area

Signal Transduction

Key Properties

• CAS Number: 2923865-76-1
• MW: 552.98
• Formula: C₂₆H₁₉ClF₂N₆O₂S
• SMILES: ClC=1C2=C3C(C(=O)N4[C@](CCN3N1)(CN(C(C=C)=O)CC4)[H])=CC(F)=C2C5=C6C(SC(N)=C6C#N)=C(F)C=C5
• Target: Ras

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Ras