Kobe2602

SKU: orb1307227

Description

Kobe 2602 is a Ras inhibitor with demonstrated anticancer properties. It is used in cancer research to study Ras-driven signaling pathways and has been evaluated in both in vitro cell-based assays and in vivo tumor model studies.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 454453-49-7
• MW: 419.31
• Purity: 98.36%
• Formula: C₁₄H₉F₄N₅O₄S
• SMILES: [O-][N+](=O)c1cc(cc(c1NNC(=S)Nc1ccc(F)cc1)[N+]([O-])=O)C(F)(F)F
• Target: Raf,Ras
• Solubility: DMSO:50 mg/mL (119.24 mM)

Bioactivity

• Target IC50:
  Ras:149 μM(Ki)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

H-Ras, inhibit, Inhibitor, Kobe 2602, Kobe2602, Kobe-2602, carcinoma, antiproliferative, Ras-Raf, Ras, Raf

Compound Identifiers

PubChem CID

3827738