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Catalog Number | orb1307283 |
---|---|
Category | Small Molecules |
Description | Kobe0065 |
CAS Number | 436133-68-5 |
Purity | 99.76% |
MW | 449.79 |
SMILES | N(NC(NC1=CC(Cl)=C(C)C=C1)=S)C2=C(N(=O)=O)C=C(C(F)(F)F)C=C2N(=O)=O |
Formula | C15H11ClF3N5O4S |
Biological Activity | Kobe0065 is a novel and effective small-molecule compound inhibiting Ras–Raf interaction by SBDD; shows potent activity to competitively inhibit the binding of H-Ras·GTP to c-Raf-1 RBD with a Ki value of 46 ± 13 μM. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
[436133-68-5] | |
449.7922 | |
C15H11CLF3N5O4S |
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