KN1022

SKU: orb1689824

Description

KN1022 is a potent small molecule inhibitor that selectively targets the platelet-derived growth factor (PDGF) receptor, blocking its phosphorylation with an IC50 of 0.26 µM. It is a valuable research tool for studying PDGF signaling pathways in cellular models and has been utilized in investigations related to fibrosis and proliferative diseases.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 205255-11-4
• MW: 438.44
• Purity: 99.88% (May vary between batches)
• Formula: C₂₁H₂₂N₆O₅
• SMILES: O(C)C1=CC=2C(=NC=NC2C=C1OC)N3CCN(C(NC4=CC=C(N(=O)=O)C=C4)=O)CC3
• Target: PDGFR
• Solubility: DMSO:11 mg/mL (25.09 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

PDGFR, KN1022, KN-1022, KN 1022

Compound Identifiers

PubChem CID

9911005