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KLHDC2-IN-1

SKU: orb3135652

Description

KLHDC2-IN-1 (Compound 6) is a ligand that specifically targets the ubiquitin E3 ligase KLHDC2 with a dissociation constant (Kd) of 160 nM. It can be synthesized into a PROTAC capable of effectively degrading BRD4 within cells.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number1005275-19-3
MW437.84
FormulaC22H19ClF3NO3
SMILESO=C(O)C1=CC(Cl)=CC2=C1NC(C=3C=CC=C(OC(F)(F)F)C3)C4C2C5CCC4C5
TargetLigands for E3 Ligase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information