Kinetin riboside

SKU: orb1299907

Description

Kinetin riboside (N6-Furfuryladenosine) is a cytokinin-derived small molecule that induces apoptosis and inhibits proliferation in cancer cells such as HCT-15 (IC50 = 2.5 µM). It serves as a research tool for studying cell death mechanisms in oncology, with applications in both in vitro and in vivo experimental models.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 4338-47-0
• MW: 347.33
• Purity: 98.17% (May vary between batches)
• Formula: C₁₅H₁₇N₅O₅
• SMILES: OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NCc3ccco3)ncnc12
• Target: Apoptosis
• Solubility: DMSO:29 mg/mL (83.49 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.76 mM)

Bioactivity

• Target IC50:
  HCT15 cells:2.5 μM
• In Vitro:
  kinetin riboside displays antiproliferative and apoptogenic activity against various human cancer cell lines and has been shown to suppress tumor growth in murine xenograft models of human leukemia and melanoma.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Apoptosis, Apoptosis inducer, Inhibitor, inhibit, Kinetin riboside, N6-Furfuryladenosine

Compound Identifiers

PubChem CID

20345