KIF18A-IN-7

SKU: orb1744473

Description

KIF18A-IN-7 is a potent, orally bioavailable small molecule inhibitor of the mitotic kinesin KIF18A, exhibiting an IC50 of 9.4 nM against its ATPase activity. This compound is a valuable chemical probe for investigating KIF18A's role in chromosome segregation and for exploring potential anticancer strategies in cellular and in vivo cancer models.

Research Area

Signal Transduction

Key Properties

• CAS Number: 2914878-00-3
• MW: 545.71
• Formula: C₂₇H₃₅N₃O₅S₂
• SMILES: C(=O)(N1CC2(C=3C1=CC=C(NS(C)(=O)=O)C3)CCC4(CC2)CC4)C5=CC(S(NC(C)(C)C)(=O)=O)=CC=C5
• Target: Kinesin,Others,Microtubule Associated

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

167493602