KIF18A-IN-2

SKU: orb1301214

Description

KIF18A-IN-2

Research Area

Signal Transduction

Key Properties

• CAS Number: 2600559-20-2
• MW: 534.69
• Purity: 99.64% (May vary between batches)
• Formula: C₂₅H₃₄N₄O₅S₂
• SMILES: CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2ccc(NS(C)(=O)=O)cc2N2CCC3(CC3)CC2)c1
• Target: Microtubule Associated,Kinesin
• Solubility: DMSO:55 mg/mL (102.86 mM)

Bioactivity

• In Vivo:
  In Female athymic nude mice injected with human OVCAR-3 HGSOC cells, KIF18A-IN-2 (100 mg/kg; i.p.) exhibits a significant and sustained pharmacodynamic response and increases the number of mitotic cells (pH3 positive cells) in tumor tissues.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Mitotic, mitotic kinesin Kif18A, Microtubule, Microtubule Associated, Microtubule/Tubulin, MicrotubuleAssociated, inhibit, KIF18A, KIF18A IN 2, KIF18AIN2, KIF18A-IN-2, Inhibitor, Cancer, OVCAR-3, Tubulin

Compound Identifiers

PubChem CID

155780983