KHKI-01215

SKU: orb2815824

Description

KHKI-01215 is a potent and selective NUAK2 inhibitor developed for cancer research. It demonstrates anticancer activity by suppressing proliferation and inducing apoptosis in SW480 colorectal cancer cells in vitro, supporting investigations into NUAK2's role in tumorigenesis.

Research Area

Cell Biology, Stem Cell & Developmental Biology

Key Properties

• MW: 598.4
• Purity: 98.19% (May vary between batches)
• Formula: C₂₄H₂₆F₃IN₆O
• SMILES: CN(C)C1=CC=CC(OC2=NC(NC3=CC(C(F)(F)F)=C(N4CCN(C)CC4)C=C3)=NC=C2I)=C1
• Target: Apoptosis,YAP

Bioactivity

• Target IC50:
  NUAK2:0.052 μM
• In Vitro:
  KHKI-01215 is an inhibitor of NUAK2 with IC50 of 0.052 μM. KHKI-01215 inhibited the proliferation of cancer cell SW480 with IC50 of 3.16 μM.

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

KHKI01215

Compound Identifiers

PubChem CID

172419084