Queen's Award Received in 2021 ISO 9001 Certified Delivered over 1,000,000 bio-reagents to life science researchers Trusted by Life Science Communities
Cart summary

You have no items in your shopping cart.

Kevetrin

SKU: orb3210607

Description

Kevetrin (3-Cyanopropyl carbamimidothioate; 4-Isothioureidobutyronitrile) is an apoptosis inducer that exhibits both p53-dependent and p53-independent anti-tumor activity. In TP53 wild-type models, Kevetrin activates and stabilizes the p53 protein by altering the processing of MDM2, leading to cell cycle arrest and apoptosis. It shows increased sensitivity in mutant models. Kevetrin is applicable for research in various cancers, including acute myeloid leukemia and breast cancer.

Images & Validation

Key Properties

CAS Number500863-50-3
MW143.21
FormulaC5H9N3S
SMILESN#CCCCSC(=N)N
TargetMDM-2/p53,Apoptosis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Similar Products

  • Kevetrin hydrochloride [orb1304449]

    99.93% (May vary between batches)

    66592-89-0

    179.67

    C5H10ClN3S

    10 mg, 25 mg, 50 mg, 100 mg, 1 ml x 10 mM (in DMSO), 5 mg
  • Kevetrin hydrochloride [orb1223081]

    >98% (HPLC)

    66592-89-0

    179.67

    C5H10ClN3S

    5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 200 mg, 500 mg, 1 g
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Protocol Information