Ketanserin tartrate

SKU: orb1710164

Description

Ketanserin tartrate (KJK-945 tartrate) is a selective antagonist of the 5-HT2A receptor and α1-adrenergic receptor. It is utilized in research on hypertension, serotonin-mediated vasoconstriction, and platelet aggregation, with applications in studying systemic sclerosis in both in vitro and in vivo models.

Research Area

Cell Biology, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 83846-83-7
• MW: 545.51
• Purity: 99.68%
• Formula: C₂₆H₂₈FN₃O₉
• SMILES: O[C@H]([C@@H](O)C(O)=O)C(O)=O.Fc1ccc(cc1)C(=O)C1CCN(CCn2c(=O)[nH]c3ccccc3c2=O)CC1
• Target: Autophagy,Adrenergic Receptor,5-HT Receptor,Serotonin Transporter,Potassium Channel
• Solubility: H2O:< 0.1 mg/mL (insoluble.);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.67 mM);DMSO:15 mg/mL (27.5 mM)

Bioactivity

• Target IC50:
  K+ channel (hERG):0.11 μM

Storage & Handling

• Storage: keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

5HT Receptor, 5-HT2A, AdrenergicReceptor, Adrenergic Receptor, 5HTReceptor, KJK 945, KJK 945 tartrate, KJK945, KJK-945, KJK945 tartrate, KJK-945 tartrate, α1-adrenergic receptor, R 49945, R49945, R-49945, SerotoninTransporter, Serotonin Transporter, serotonin

Compound Identifiers

PubChem CID

16219944