Ketanserin tartrate

SKU: orb1710164

Description

Ketanserin tartrate (KJK-945 tartrate) is a selective antagonist of the 5-HT2A receptor and α1-adrenergic receptor. It is utilized in research on hypertension, serotonin-mediated vasoconstriction, and platelet aggregation, with applications in studying systemic sclerosis in both in vitro and in vivo models.

Research Area

Neuroscience

Key Properties

• CAS Number: 83846-83-7
• MW: 545.5
• Purity: >98%
• Formula: C₂₂H₂₂FN₃O₃ • C₄H₆O₆
• SMILES: O[C@H]([C@@H](O)C(O)=O)C(O)=O.Fc1ccc(cc1)C(=O)C1CCN(CCn2c(=O)[nH]c3ccccc3c2=O)CC1
• Target: Monoamine receptor
• Solubility: Soluble in DMSO (up to 30 mg/ml) or in Water (up to 5 mg/ml).

Bioactivity

• Target IC50:
  K+ channel (hERG):0.11 μM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

R41468

Compound Identifiers

PubChem CID

16219944