KEAP1-NRF2 PPI-IN-1

SKU: orb2944870

Description

KEAP1-NRF2PPI-IN-1 (compound 23) is a small molecule inhibitor that disrupts the KEAP1-NRF2 protein-protein interaction. It demonstrates inhibitory activity with IC50 values of 136 nM in human TK6 cells and 62 nM in insect SF9 cells in DNA damage assays, supporting its use in research on oxidative stress and cytoprotection pathways.

Research Area

Immunology & Inflammation

Images & Validation

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Key Properties

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MW	478.01
Formula	C₁₇H₂₀ClN₃O₅S₃
Target	Nrf2

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Gene Symbol

Nrf2

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