KEAP1-NRF2 PPI-IN-1

SKU: orb2944870

Description

KEAP1-NRF2PPI-IN-1 (compound 23) is a small molecule inhibitor that disrupts the KEAP1-NRF2 protein-protein interaction. It demonstrates inhibitory activity with IC50 values of 136 nM in human TK6 cells and 62 nM in insect SF9 cells in DNA damage assays, supporting its use in research on oxidative stress and cytoprotection pathways.

Research Area

Cancer Biology, Immunology & Inflammation

Key Properties

• MW: 478.01
• Formula: C₁₇H₂₀ClN₃O₅S₃
• Target: Nrf2

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Nrf2