Keap1-Nrf2-IN-14

SKU: orb1686053

Description

Keap1-Nrf2-IN-14 is a potent small molecule inhibitor of the KEAP1-NRF2 interaction with an IC50 of 75 nM, disrupting this pathway to modulate oxidative stress responses. It is utilized in both in vitro and in vivo research models to investigate conditions involving inflammation, neurodegeneration, and chemoresistance linked to NRF2 signaling.

Research Area

Cancer Biology, Immunology & Inflammation, Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 1928782-31-3
• MW: 563.62
• Formula: C₃₀H₂₉NO₈S
• SMILES: N(S(=O)(=O)C1=C(C)C=C(C)C=C1C)(CC(O)=O)C=2C3=C(C(OC(C(O)=O)C4=CC=C(OC)C=C4)=CC2)C=CC=C3
• Target: Others,Reactive Oxygen Species,Nrf2

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

154584181