Keap1-Nrf2-IN-13

SKU: orb1744723

Description

Keap1-Nrf2-IN-13 is a potent and specific inhibitor of the Keap1-Nrf2 protein-protein interaction (IC50 = 0.15 µM), binding via key hydrogen bonds. Its mechanism makes it a valuable research tool for studying oxidative stress and inflammation in diseases such as pulmonary fibrosis, COPD, and cancer in both cellular and animal models.

Research Area

Cancer Biology, Immunology & Inflammation

Key Properties

• CAS Number: 2456294-92-9
• MW: 620.69
• Formula: C₂₈H₃₂N₂O₁₀S₂
• SMILES: N(S(=O)(=O)C1=CC=C(OC)C=C1)(CC2=C(CN(S(=O)(=O)C3=CC=C(OC)C=C3)[C@H](C(O)=O)C)C=CC=C2)[C@H](C(O)=O)C
• Target: Nrf2

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

156015932