KEA1-97

SKU: orb1298354

Description

KEA1-97

Research Area

Cell Biology, Protein Biochemistry

Key Properties

• CAS Number: 2138882-71-8
• MW: 335.16
• Purity: 98.70% (May vary between batches)
• Formula: C₁₅H₉Cl₂FN₄
• SMILES: Fc1ccc(cc1)-c1ccc(Nc2nc(Cl)nc(Cl)n2)cc1
• Target: Apoptosis,Caspase
• Solubility: DMSO:90 mg/mL (268.53 mM);10% DMSO+90% Corn Oil:3.3 mg/mL (9.85 mM)

Bioactivity

• Target IC50:
  Thiordoxine:10μM|Caspase-3:10μM
• In Vivo:
  KEA1–97 treatment (5 mg/kg ip once per day) was initiated 16 days after the initiation of 231MFP tumor xenografts in immune-deficient SCID mice.
• In Vitro:
  KEA1-97 (10 μM, 48h) impaired 231MFP cell survival and proliferation and does not affect viability in MCF10A cells.

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

DCTalkyne, Inhibitor, KEA1 97, KEA197, KEA-1-97, KEA1-97, inhibit, 231MFP, Apoptotic, Apoptosis, Caspase, Caspase-3, Proliferation, Selective, Thiordoxine

Compound Identifiers

PubChem CID

135338301